𝔖 Bobbio Scriptorium
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IgE-mediated fungal allergy in allergic fungal sinusitis

✍ Scribed by Harshita Pant; Mark A. Schembri; Peter J. Wormald; Peter J. Macardle

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
97 KB
Volume
119
Category
Article
ISSN
0023-852X

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✦ Synopsis

Abstract

This review will address the current knowledge of the pathogenic mechanisms in allergic fungal sinusitis (AFS) and the basis for the current classification of a subgroup of chronic rhinosinusitis patients. Special attention is directed to the role of immunoglobulin E (IgE)‐mediated fungal allergy in the pathogenesis of AFS. Concepts relating to the mucosal inflammatory response are introduced, as a knowledge of the reactions of the sinus mucosal cells can lead to a better understanding of the mechanisms perpetuating and maintaining the chronic inflammation. Laryngoscope, 2009

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