Ifosfamide, methotrexate, and 5-fluorouracil: effective combination in resistant breast cancer
โ Scribed by N. Gad-El-Mawla; M. R. Hamza; Z. K. Zikri; M. Elserafi; A. El-Khodari; H. Khaled; R. Gafaar
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 200 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0344-5704
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Twenty-nine patients with metastatic breast cancer were treated with fluorouracil, adriamycin, cyclophosphamide (FAC), and methotrexate (MTX), with or without leukovorin rescue. Of 24 evaluable patients, one achieved a complete remission and 17 had partial responses. The overall objective response r
A low-dose, three-drug regimen, C.M.F. (cyclophosphamide 50 mg, P.o., days 1-14; methotrexate, 25 mg, and 5-fluorouracil, 500 mg, i.v., days 1 and 8; cycled every 28 days) was used in 46 consecutive chemotherapy-eligible women (41 previously hormonally treated) with recurrent breast cancer. Thirteen