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IFNL3 (IL28B) and IFNL4 polymorphisms are associated with treatment response in Thai patients infected with HCV genotype 1, but not with genotypes 3 and 6

✍ Scribed by Akkarathamrongsin, Srunthron; Thong, Vo Duy; Payungporn, Sunchai; Poovorawan, Kittiyod; Prapunwattana, Phisit; Poovorawan, Yong; Tangkijvanich, Pisit


Book ID
127128230
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
231 KB
Volume
86
Category
Article
ISSN
0146-6615

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IL28B genetic variation and treatment re
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Polymorphisms near the IL28B gene, which code for interferon (IFN)-Ξ»3, predict response to pegylated interferon-Ξ± (PEG-IFN) and ribavirin treatment in hepatitis C virus (HCV) genotype 1 infected patients. Follow-up studies of the effect of IL28B gene in HCV non-genotype 1 infected patients have almo