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IFN-γ down-regulates TGF-β1-induced IgA expression through Stat1 and p300 signaling

✍ Scribed by Seok-Rae Park; Mee-Hyeun Jung; Seong-Hyun Jeon; Mi-Hee Park; Kyoung-Hoon Park; Mi-Ra Lee; Pyeung-Hyeun Kim


Book ID
106263017
Publisher
Korean Society for Molecular and Cellular Biology
Year
2009
Tongue
English
Weight
308 KB
Volume
29
Category
Article
ISSN
1016-8478

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## Abstract Retinal pigment epithelium (RPE) and transforming growth factor‐β (TGF‐β) have been shown to be involved in various retinal diseases. We have studied the role of inflammatory cytokines on the expression and secretion of TGF‐β in human RPE cells (HRPE). Confluent cultures of HRPE derived