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IFN-β Gene Therapy Induces Systemic Antitumor Immunity Against Malignant Glioma

✍ Scribed by Atsushi Natsume; Kunio Tsujimura; Masaaki Mizuno; Toshitada Takahashi; Jun Yoshida


Book ID
110235457
Publisher
Springer US
Year
2000
Tongue
English
Weight
73 KB
Volume
47
Category
Article
ISSN
0167-594X

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## Abstract Interferon‐β (IFN‐β) has been used as an antitumor drug against human glioma, melanoma and medulloblastoma since the 1980s. Recently, we developed a new gene therapy using the __IFN__‐β gene against malignant gliomas and then began clinical trials in 2000. Since stimulation of immune sy