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iDQC MRI weighted by longitudinal relaxation in the rotating frame

✍ Scribed by Bingwen Zheng; Zhong Chen; Scott D. Kennedy; Jianhui Zhong

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
435 KB
Volume
56
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

A long‐duration, low‐power, off‐resonance spin‐locking pulse was incorporated into the COSY revamped by asymmetric z gradient‐echo detection (CRAZED) pulse sequence in order to evaluate the effects of intermolecular double‐quantum longitudinal relaxation in the tilted rotating frame (T). This modified CRAZED sequence was followed by a standard fast spin‐echo imaging sequence to form images with T‐weighted contrast. Imaging experiments were performed on an agarose‐gel phantom and mouse‐tail tissue at 600 MHz. Experimental results demonstrated the feasibility of imaging applications based on T as a novel contrast mechanism, and showed that iDQC off‐resonance longitudinal relaxation in the rotating frame T is sensitive to the tilt angle θ and the effective spin‐locking field ωe. Imaging based on T has reduced RF power deposition compared to on‐resonance spin‐locking, which is advantageous for human applications. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.

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