Idoxuridine—a preliminary report
✍ Scribed by Louis J. Ravin; Charles A. Simpson; Alfred F. Zappala
- Publisher
- John Wiley and Sons
- Year
- 1964
- Tongue
- English
- Weight
- 93 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
✦ Synopsis
Data are presented to show that the rincipal decomposition products of idoxuricfke ophthalmic solution in acidic media (PH 1.3 to 6.7) are 5-iodouracil and 2-deoxyribose. A trace of Z'-deoxyuridine was also detected.
Uracil was not formed under the conditions of these experiments.
📜 SIMILAR VOLUMES
Data are presented for the hydrolytic degradation of idoxuridine (5-iodo-2 '-deoxyuridine) in aqueous solution over a wide range of hydrogen ion concentration (pH 1.3 to 12.0). The over-all reaction rate was experimentally equal to R, '' K, + IH+l idoxuridine at p H 6.0 was found to be approximately
## Abstract L‐asparaginase, an enzyme used in the treatment of leukemia, has been covalently coupled to a Dacron vascular prothesis. The enzyme activity was determined __in vitro__ and after remaining 7 days __in vivo__.