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Idiotypic oligonucleotide probes to detect myeloma cells by mRNA in situ hybridization

โœ Scribed by Ross BROWN; XIAO-FENG LUO; JOHN GIBSON; ALEC MORLEY; PAM SYKES; MICHAEL BRISCO; DOUG JOSHUA


Book ID
114714075
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
551 KB
Volume
90
Category
Article
ISSN
0007-1048

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Individual myeloma cells in the peripheral blood of 7 patients with multiple myeloma were detected by mRNA in situ hybridization (ISH) using biotinylated antisense oligonucleotide probes to non-germline sequences of the CDR3 region of the immunoglobulin heavy chain gene. Peripheral blood samples fro