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✦   LIBER   ✦

Idiopathic giant cell myocarditis after autologous hematopoietic stem cell transplantation and interleukin-2 immunotherapy : A case report

✍ Scribed by Cristina I. Truica; Christian H. Hansen; David F. Garvin; Kenneth R. Meehan

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
691 KB
Volume
83
Category
Article
ISSN
0008-543X

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✦ Synopsis

BACKGROUND.

Interleukin-2 (IL-2) is used in the treatment of solid tumors and hematologic malignancies. Sudden death is a rare complication of IL-2 treatment.

METHODS.

A patient with lymphoma underwent chemoradiotherapy myeloablation and autologous stem cell transplantation. The stem cells were cultured in IL-2 (6000 IU/mL) for 24 hours prior to infusion. After engraftment, treatment with IL-2 (1.8 Ο« 10 6 IU/m 2 /day administered subcutaneously) was begun. After 4 days of treatment, the patient suddenly died. An autopsy was performed.

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