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Idiopathic Budd–Chiari syndrome in a patient with homozygous Factor V Leiden and heterozygous Factor II G20210A mutations

✍ Scribed by Valentino De Stefano; Pasquale Madonna; Alessandro Giannino; Antonio Coppola; Anna Maria Cerbone; Paolo Pauciullo; Giovanni Di Minno

Book ID: 117256900
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 41 KB
Volume: 100
Category: Article
ISSN: 0049-3848
DOI: 10.1016/s0049-3848(00)00355-8

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Budd-Chiari syndrome is characterized by hepatic venous outflow obstruction. Although myeloproliferative disorders are usually responsible for this severe thrombotic disorder, deficiency or dysfunction of the natural anticoagulants can be involved. Resistance to activated protein C caused by factor