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IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis

✍ Scribed by Castagnetti, F; Rosti, G; Soverini, S; Score, J; Iacobucci, I; Poerio, A; Lonetti, A; Gnani, A; Colarossi, S; Ferrari, A

Book ID: 109887267
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 245 KB
Volume: 25
Category: Article
ISSN: 0887-6924
DOI: 10.1038/leu.2010.236

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## Abstract Chronic myeloid leukemia is a myeloproliferative disorder characterized by the presence of the Philadelphia chromosome, t(9:22). Extramedullary blast crisis is a rare event. Imatinib mesylate has become the treatment of choice, especially for patients for whom allogenic stem cell transp