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IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

✍ Scribed by Qi SongTao; Yu Lei; Gui Si; Ding YanQing; Han HuiXia; Zhang XueLin; Wu LanXiao; Yao Fei

Book ID: 114703117
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 173 KB
Volume: 103
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2011.02134.x

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## Abstract Recently, mutations in the __epidermal growth factor receptor__ (__EGFR__) gene in nonsmall cell lung cancer (NSCLC) patients were reported to correlate with gefitinib response. Less than 30% of NSCLC patients are surgically resectable; however, molecular analysis has to rely on nonsurg