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Identifying the Regulative Role of NF-κB Binding Sites Within Promoter Region of Human Matrix Metalloproteinase 9 (mmp-9) by TNF-α Induction

✍ Scribed by Hsi Tien Wu, Syu Sheng Sie, Tang Ching Kuan, Chih Sheng Lin

Book ID: 118820608
Publisher: Springer-Verlag
Year: 2012
Tongue: English
Weight: 593 KB
Volume: 169
Category: Article
ISSN: 0273-2289
DOI: 10.1007/s12010-012-9958-3

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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor