hTERT gene copy number is not associated
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Richard Palmqvist; Anju Zhang; Dawei Xu; Irina Golovleva; Karl-Fredrik Norrback;
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Article
📅
2005
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John Wiley and Sons
🌐
French
⚖ 735 KB
## Abstract In a majority of malignant human tumors telomerase activity can be detected, suggesting an immortal phenotype. Expression of the reverse transcriptase subunit, hTERT, in the human telomerase complex is required for telomerase activity. The regulation of hTERT, from gene level to a fully