𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Identifying agonistic and antagonistic mechanisms operative at the GABA receptor

✍ Scribed by Professor E. Galvez-Ruano; Prof. M. H. Aprison; D. H. Robertson; K. B. Lipkowitz

Book ID
118284651
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
725 KB
Volume
42
Category
Article
ISSN
0360-4012

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

On identifying a second molecular antago
On identifying a second molecular antagonistic mechanism operative at the glycine receptor
✍ E. Galvez-Ruano; K. B. Lipkowitz; Prof. M. H. Aprison πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 578 KB

We used molecular modeling techniques to examine six reported antagonists of glycine with varying K, values against strychnine. We found the data suggest two groups operating with different mechanisms. In group 1 (strychnine, brucine, Pitrazepin, and bicuculline methobromide) the antagonist contains