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Identification of tyrosine as a functional residue in the active site of Escherichia coli dUTPase

✍ Scribed by Beata G. Vertessy; Petra Zalud; Per O. Nyman; Michael Zeppezauer


Book ID
113269406
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
402 KB
Volume
1205
Category
Article
ISSN
0167-4838

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## Abstract Treatment of the Class II fructose‐1,6‐bisphosphate aldolase of __Escherichia coli__ with the arginine‐specific α‐dicarbonyl reagents, butanedione or phenylglyoxal, results in inactivation of the enzyme. The enzyme is protected from inactivation by the substrate, fructose 1,6‐bisphospha