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Identification of Two Regions in the Cytoplasmic Domain of CD44 through Which PMA, Calcium, and Foskolin Differentially Regulate the Binding of CD44 to Hyaluronic Acid

โœ Scribed by Dacai Liu; Tong Liu; Man-Sun Sy


Book ID
112240025
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
380 KB
Volume
190
Category
Article
ISSN
0008-8749

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CD44 isoforms, such as CD44s (the standard form), contain at least one ankyrin-binding site within the 70-amino acid (aa) cytoplasmic domain and several hyaluronic acid (HA)-binding sites within the extracellular domain. To study the role of CD44s-ankyrin interaction in regulating human prostate tum