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Identification of Two Penicillin-Binding Multienzyme Complexes in Haemophilus influenzae

✍ Scribed by Armin Alaedini; Richard A. Day


Book ID
115584605
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
70 KB
Volume
264
Category
Article
ISSN
0006-291X

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Molecular modelling of trimethoprim comp
✍ Ran Pan; Donnell Bowen; William M. Southerland πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 426 KB

Computer-assisted molecular modelling was used to generate structures for the trimethoprim (TMP):NADPH:dihydrofolate reductase (DHFR) ternary complexes for human wild-type DHFR and for five DHFR mutants (L22R, L22F, F31S, F31W and Q35P). The mutants correspond to DHFR proteins that have been isolate