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Identification of Two Gene Variants Associated With Risk of Advanced Fibrosis in Patients With Chronic Hepatitis C

โœ Scribed by Hongjin Huang; Mitchell L. Shiffman; Ramsey C. Cheung; Thomas J. Layden; Scott Friedman; Olivia T. Abar; Linda Yee; Anand P. Chokkalingam; Steven J. Schrodi; Jason Chan; Joseph J. Catanese; Diane U. Leong; David Ross; Xiaolan Hu; Alexander Monto; Linda B. McAllister; Samuel Broder; Thomas White; John J. Sninsky; Teresa L. Wright


Book ID
119759158
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
223 KB
Volume
130
Category
Article
ISSN
0016-5085

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Keratin variants associate with progress
โœ Pavel Strnad; Tim C. Lienau; Guo-Zhong Tao; Laura C. Lazzeroni; Felix Stickel; D ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 845 KB

Keratins 8 and 18 (K8/K18) protect the liver from various forms of injury. Studies of liver explants from a large cohort of U.S. patients showed that K8/K18 mutations confer a risk to developing end-stage liver diseases, though which diseases are preferentially involved is unknown. We tested the hyp