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Identification of Two Distinct Structural Transitions in the Dissociation of Peptides from Class II Proteins of the Major Histocompatibility Complex

โœ Scribed by McFarland, Benjamin J.; Sant, Andrea J.; Beeson, Craig


Book ID
125953010
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
32 KB
Volume
121
Category
Article
ISSN
0002-7863

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โœ Benjamin J. McFarland; Craig Beeson ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 464 KB

## Abstract The activation of helper T cells by peptides bound to proteins of the class II Major Histocompatibility Complex (MHC II) is pivotal to the initiation of an immune response. The primary functional requirement imposed on MHC II proteins is the ability to efficiently bind thousands of diff