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Identification of Tumor Suppressor Genes by Microcell Hybridization

โœ Scribed by Bernard E. Weissman; Daniel Gioeli; Karen Phillips

Book ID
115638630
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
229 KB
Volume
9
Category
Article
ISSN
1046-2023

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## Abstract Tumor suppressor genes (TSGs) are sometimes inactivated by transcriptional silencing through promoter hypermethylation. To identify novel methylated TSGs in melanoma, we carried out global mRNA expression profiling on a panel of 12 melanoma cell lines treated with a combination of 5โ€Aza