## Abstract All human T lymphoblast cell lines have been derived from subjects with leukemia secondary to thymic lymphoblastic lymphoma, a T cell malignacy, suggesting that such lines represent established cultures of neoplastic T cells. Based on this observation, we prepared rabbit antisera to T c
Identification of tumor antigens and T-cell epitopes, and its clinical application
β Scribed by Annette Paschen; Stefan Eichmuller; Dirk Schadendorf
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 172 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Microsatellite instability (MSI) caused by defective DNA mismatch repair (MMR) is a hallmark of hereditary nonpolyposis colorectal cancers (HNPCC) but also occurs in about 15% of sporadic tumors. If instability affects microsatellites in coding regions, translational frameshifts lead to truncate
## Abstract SSX2 is a member of the family of cancer/testis antigens. The SSX2 derived peptide SSX2~103β111~ has been shown to be presented to cytotoxic Tβlymphocytes (CTL) by MajorβHistocompatibility (MHC) ClassβI complexes after endogenous processing, more precisely by the allele HLAβA\*0201. The
## Abstract In previous studies CD8+ T cells specific for melanocyte antigens have been frequently found in melanoma patients responding to interleukinβ2 (ILβ2)βbased therapies. In our study we analyzed the suitability of using circulating T cells from melanoma patients with clinical response after