Identification of a novel RAS GTPase-act
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Anne R. M. von Bergh; Pauline M. Wijers; Arjan J. Groot; Shama van Zelderen-Bhol
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Article
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2004
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John Wiley and Sons
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English
⚖ 209 KB
The t(9;11) has been described in patients with acute myeloid leukemia (AML), and two genes [AF9 (at 9p21) and FBP17 (at 9q34)] have been cloned as fusion partners of the MLL gene. From an AML-M5 with a t(9;11)(q34;q23), we identified a novel MLL fusion partner, AF9Q34. The AF9Q34 protein shows high