✦ LIBER ✦

Identification of three missense mutations in the peroxisome proliferator-activated receptor α gene in Japanese subjects with maturity-onset diabetes of the young

✍ Scribed by M. Hara; X. Wang; V. P. Paz; N. Iwasaki; M. Honda; Y. Iwamoto; G. I. Bell

Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 60 KB
Volume: 46
Category: Article
ISSN: 1435-232X
DOI: 10.1007/s100380170080

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Three novel missense mutations in the gl

Three novel missense mutations in the glucokinase gene (G80S; E221K; G227C) in Italian subjects with maturity-onset diabetes of the young (MODY)

✍ Barbara Guazzini; Davide Gaffi; Davide Mainieri; Giuseppe Multari; Renzo Cordera 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 30 KB 👁 1 views

The maturity-onset diabetes of the young (MODY), an autosomal dominant form of non-insulin dependent diabetes mellitus (NIDDM), is caused by mutations in the glucokinase (GK, MODY 2) and in the hepatocyte nuclear factor 1 (MODY 3) and 4 (MODY1) genes. We have screened the glucokinase gene by the pol

Identification of missense mutations in

Identification of missense mutations in the hepatocyte nuclear factor-3β gene in Japanese subjects with late-onset Type II diabetes mellitus

✍ Q. Zhu; K. Yamagata; L. Yu; H. Tomura; S. Yamada; Q. Yang; I. Yoshiuchi; S. Sumi 📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 74 KB

Identification of eight novel glucokinas

Identification of eight novel glucokinase mutations in Italian children with maturity-onset diabetes of the young

✍ Vilma Mantovani; Silvana Salardi; Vincenzo Cerreta; Daniela Bastia; Marinella Ce 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 35 KB 👁 2 views

## Maturity -onset diabetes of the young (MODY) is a clinically heterogeneous group of disorders characterized by early onset non-insulin-dependent diabetes mellitus, autosomal dominant inheritance, and primary defect in the function of the beta cells of the pancreas. Mutations in the glucokinase

A missense mutation in the hepatocyte nu

A missense mutation in the hepatocyte nuclear factor 4 alpha gene in a UK pedigree with maturity-onset diabetes of the young

✍ M. P. Bulman; M. J. Dronsfield; T. Frayling; M. Appleton; S. C. Bain; S. Ellard; 📂 Article 📅 1997 🏛 Springer 🌐 English ⚖ 145 KB

Cloning of cDNA and the gene encoding hu

Cloning of cDNA and the gene encoding human hepatocyte nuclear factor (HNF)-3βand mutation screening in Japanese subjects with maturity-onset diabetes of the young

✍ S. Yamada; Q. Zhu; Y. Aihara; H. Onda; Z. Zhang; L. Yu; L. Jin; Y. -J. Si; H. Ni 📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 85 KB

Identification of 21 novel glucokinase (

Identification of 21 novel glucokinase (GCK) mutations in UK and European Caucasians with maturity-onset diabetes of the young (MODY)

✍ K.L. Thomson; A.L. Gloyn; K. Colclough; M. Batten; L.I.S. Allen; F. Beards; A.T. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 32 KB 👁 2 views

## Maturity -onset diabetes of the young (MODY) resulting from mutations in the glucokinase (GCK) gene accounts for approximately 20% of MODY in the UK. W e have performed fluorescent single stranded conformation polymorphism (F-SSCP) analysis or direct sequencing of the GCK gene in 212 patients re