The efficient stereoselective synthesis
✍
Shigekazu Sasaki; Yasumasa Hamada; Takayuki Shioiri
📂
Article
📅
1999
🏛
Elsevier Science
🌐
French
⚖ 216 KB
The title acid, a component of microsclerodermins of marine sponge origin having five consecutive stereogenic centers, was efficiently synthesized as its protected form 1 from the alcohol 5 utilizing the stereoselective addition of anisole to the acetylenic triple bond and the anti-aldol reaction as