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Identification of the S3–S4 dimer, as component of pertussis toxin which protects against EAE

✍ Scribed by R. Latif; N. Kerlero de Rosbo; A. Ben-Nun


Book ID
114138594
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
123 KB
Volume
90
Category
Article
ISSN
0165-5728

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The title acid, a component of microsclerodermins of marine sponge origin having five consecutive stereogenic centers, was efficiently synthesized as its protected form 1 from the alcohol 5 utilizing the stereoselective addition of anisole to the acetylenic triple bond and the anti-aldol reaction as