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Identification of the microtubule-associated protein map2and its binding sites on metaphase chromosomes from cultured cells

✍ Scribed by Francisco Wandosell; Antonio Rodríguez-Campos; José Fernández Piqueras; Jesús Avila


Publisher
Springer
Year
1984
Tongue
English
Weight
833 KB
Volume
90
Category
Article
ISSN
0009-5915

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✦ Synopsis


The microtubule-associated protein MAP2, which binds preferentially to AT sequences of DNA, can bind to metaphase chromosomes. The binding pattern of MAP2 to chromosomes is similar to that found for the binding of the bisbenzimidazole derivative 33258 Hoechst, which also binds preferentially to AT-rich regions.


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