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Identification of the ligand binding sites on the molecular surface of proteins

✍ Scribed by Kengo Kinoshita; Haruki Nakamura


Book ID
119824397
Publisher
Cold Spring Harbor Laboratory Press
Year
2005
Tongue
English
Weight
233 KB
Volume
14
Category
Article
ISSN
0961-8368

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Prediction of ligand-binding sites of pr
✍ Yoshifumi Fukunishi; Haruki Nakamura πŸ“‚ Article πŸ“… 2010 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 195 KB

## Abstract A new approach to predicting the ligand‐binding sites of proteins was developed, using protein‐ligand docking computation. In this method, many compounds in a random library are docked onto the whole protein surface. We assumed that the true ligand‐binding site would exhibit stronger af