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Identification of the in vivo truncation sites at the C-terminal region of alpha-A crystallin from aged bovine and human lens

โœ Scribed by Takemoto, Larry J.


Book ID
115510435
Publisher
Informa plc
Year
1995
Tongue
English
Weight
170 KB
Volume
14
Category
Article
ISSN
6854-1423

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A partial clone of caldesmon, coding for the C-terminal 288 amino acids, was isolated from a human fetal liver cDNA library and sequenced. Expression of the clone in Escherichia coli produced a peptide called H1 (M r 32 549), which inhibited tropomyosin-enhanced actomyosin Mg2+-ATPase activity by 90