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Identification of the genes affecting the regulation of riboflavin synthesis in the flavinogenic yeast Pichia guilliermondii using insertion mutagenesis

✍ Scribed by Yuriy R. Boretsky; Yuriy V. Pynyaha; Volodymyr Y. Boretsky; Dariya V. Fedorovych; Lyubov R. Fayura; Olha Protchenko; Caroline C. Philpott; Andriy A. Sibirny

Book ID
109295782
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
242 KB
Volume
11
Category
Article
ISSN
1567-1356

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## Abstract Iron deficiency causes oversynthesis of riboflavin in several yeast species, known as flavinogenic yeasts. However, the mechanisms of such regulation are not known. We found that mutations causing riboflavin overproduction and iron hyperaccumulation (__rib80, rib81__ and __hit1__), as w