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Identification of the Gene Whose Mutation Leads to the Appearance of Recessive Lethal Germlings inArabidopsis thaliana

✍ Scribed by O. A. Ogarkova; A. A. Tomilov; N. B. Tomilova; V. A. Tarasov


Publisher
Springer
Year
2005
Tongue
English
Weight
65 KB
Volume
36
Category
Article
ISSN
1062-3604

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Mutations in the gene encoding fibrillin-1 (FBN1) cause Marfan syndrome (MFS) and other related connective tissue disorders. In this study we performed SSCP to analyze all 65 exons of the FBN1 gene in 76 patients presenting with classical MFS or related phenotypes. We report 7 missense mutations, 3