Binding of monoclonal antibody 4B1 to ho
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Jianzhong Sun; Stathis Frillingos; H. Ronald Kaback
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Article
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1997
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Cold Spring Harbor Laboratory Press
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English
β 695 KB
The conformationally sensitive epitope for monoclonal antibody (mAb) 4B1, which uncouples lactose from H+ translocation in the lactose permease of Escherichia coli, is localized in the periplasmic loop between helices VII and VIII (loop VII/VIII) on one face of a short helical segment (Sun J, et al.