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Identification of the d-enantiomer of 2-hydroxyglutaric acid in glutaric aciduria type II

✍ Scribed by Hiroh Watanabe; Seiji Yamaguchi; Kayoko Saiki; Nobuo Shimizu; Toshiyuki Fukao; Naomi Kondo; Tadao Orii


Book ID
115828216
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
611 KB
Volume
238
Category
Article
ISSN
0009-8981

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## Abstract Glutaric acidemia type 1 (GA1) is an autosomal recessively inherited deficiency of glutaryl‐CoA dehydrogenase. Accumulating metabolites, 3‐hydroxyglutaric (3‐OH‐GA), glutaric (GA), and __trans__‐glutaconic (TG) acids, have been proposed to be involved in the development of the striatal