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Identification of TCR- and peptide contact residues in HLA-DR3 molecules

✍ Scribed by van Meijgaarden, K.E.; Geluk, A.; Jansen, Y.Y.R.; Karr, R.W.; de Vries, R.R.P.; Ottenhoff, T.H.M.


Book ID
122067229
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
53 KB
Volume
39
Category
Article
ISSN
0198-8859

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## Abstract Previously, we have proposed that the Ξ²1 residues 9–13, 26, 28 and 86 in HLA‐DR17, the most common subtype of DR3, might be critical for the binding of an immunodominant, mycobacterial epitope (peptide 3–13 of the 65‐kDa heat shock protein). In order to examine directly (i) which DR17 r