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Identification of T cell epitopes on human proteolipid protein and induction of experimental autoimmune encephalomyelitis in HLA class II-transgenic mice

✍ Scribed by Ashutosh K. Mangalam; Meenakshi Khare; Christopher Krco; Moses Rodriguez; Chella David


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
469 KB
Volume
34
Category
Article
ISSN
0014-2980

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Early studies of murine experimental autoimmune encephalomyelitis (EAE) induced with myelin basic protein (MBP) divide various mouse strains into either "susceptible" or "resistant" phenotypes. Resistance is defined as lack of encephalitogenic responses after active immunization or adoptive transfer