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Identification of Staphylococcus aureus surface protein SdrE as a complement factor H-binding molecule

✍ Scribed by K.M. Cunnion; J.A. Sharp; P.S. Hair; C.G. Echague; M.D. Ward; T.J. Foster; J.O. Nyalwidhe


Book ID
113805490
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
71 KB
Volume
48
Category
Article
ISSN
0161-5890

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One, two or four IgG-binding domains of the Staphylococcus aureus Protein A (SPA) were inserted into the LamB protein which was expressed under control of the tac promoter. The chimeric proteins were shown to be exposed at the cell surface by analysis of isolated outer membranes and also by testing