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Identification of RASSF8 as a candidate lung tumor suppressor gene

✍ Scribed by Falvella, F S; Manenti, G; Spinola, M; Pignatiello, C; Conti, B; Pastorino, U; Dragani, T A

Book ID
110070443
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
183 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract __Fat__, a candidate tumor suppressor in __Drosophila__, is a component of Hippo signaling pathway involved in controlling organ size. We found that a ∼3 Mbp deletion in mouse chromosome 3 caused tumorigenesis of a non‐tumorigenic mammary epithelial cell line. The expression of __Fat4__