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Identification of quantitative trait loci for growth and carcass composition in cattle

โœ Scribed by E. Casas; J. W. Keele; S. D. Shackelford; M. Koohmaraie; R. T. Stone


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
75 KB
Volume
35
Category
Article
ISSN
0268-9146

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โœฆ Synopsis


Summary

A genomic screening to detect quantitative trait loci (QTL) affecting growth, carcass composition and meat quality traits was pursued. Two hundred nineteen microsatellite markers were genotyped on 176 of 620 (28%) progeny from a Brahmanโ€ƒร—โ€ƒAngus sire mated to mostly MARC III dams. Selective genotyping, based on retail product yield (%) and fat yield (%), was used to select individuals to be genotyped. Traits included in the study were birth weight (kg), hot carcass weight (kg), retail product yield, fat yield, marbling score (400โ€ƒ=โ€ƒslight^00^ and 500โ€ƒ=โ€ƒsmall^00^), USDA yield grade, and estimated kidney, heart and pelvic fat (%). The QTL were classified as significant when the expected number of false positives (ENFP) was less than 0.05 (Fโ€statistic greater than 17.3), and suggestive when the ENFP was <1 (Fโ€statistic between 10.2 and 17.3). A significant QTL (Fโ€ƒ=โ€ƒ19; ENFPโ€ƒ=โ€ƒ0.02) was detected for marbling score at centimorgan (cM) 54 on chromosome 2. Suggestive QTL were detected for fat yield at 50โ€ƒcM, for retail product yield at 53โ€ƒcM, and for USDA yield grade at 63โ€ƒcM on chromosome 1, for marbling score at 56โ€ƒcM, for retail product yield at 70โ€ƒcM, and for estimated kidney, heart and pelvic fat at 79โ€ƒcM on chromosome 3, for marbling score at 44โ€ƒcM, for hot carcass weight at 49โ€ƒcM, and for estimated kidney, heart and pelvic fat at 62โ€ƒcM on chromosome 16, and for fat yield at 35โ€ƒcM on chromosome 17. Two suggestive QTL for birth weight were identified, one at 12โ€ƒcM on chromosome 20 and the other at 56โ€ƒcM on chromosome 21. An additional suggestive QTL was detected for retail product yield, for fat yield, and for USDA yield grade at 26โ€ƒcM on chromosome 26. Results presented here represent the initial search for quantitative trait loci in this family. Validation of detected QTL in other populations will be necessary.


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