Identification of putative insulin-like peptides and components of insulin signaling pathways in parasitic platyhelminths by the use of genome-wide screening

Glucagon-like peptide-1 receptor is pres

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

✍ Nitika Arora Gupta; Jamie Mells; Richard M. Dunham; Arash Grakoui; Jeffrey Handy 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 538 KB

Glucagon-like peptide 1 (GLP-1) is a naturally occurring peptide secreted by the L cells of the small intestine. GLP-1 functions as an incretin and stimulates glucose-mediated insulin production by pancreatic beta cells. In this study, we demonstrate that exendin-4/GLP-1 has a cognate receptor on hu