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Identification of putative hypermethylation-inactivated tumor suppressor genes in HNSCC

โœ Scribed by Michael M. Kim; Patrick K. Ha; Zhongmin Guo; Nicole Benoit; Keishi Yamashita; Joseph Califano; David Sidransky

Book ID
117399651
Publisher
SAGE Publications
Year
2003
Tongue
English
Weight
40 KB
Volume
129
Category
Article
ISSN
0194-5998

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## Abstract Tumor suppressor genes (TSGs) are sometimes inactivated by transcriptional silencing through promoter hypermethylation. To identify novel methylated TSGs in melanoma, we carried out global mRNA expression profiling on a panel of 12 melanoma cell lines treated with a combination of 5โ€Aza