Identification of dihydropyrimidinase-re
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Junko Kimura; Takuya Kudoh; Yoshio Miki; Kiyotsugu Yoshida
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Article
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2010
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John Wiley and Sons
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French
⚖ 690 KB
## Abstract The p53 tumor suppressor gene, which is frequently mutated in a wide variety of tumors, plays an important role in maintaining genomic integrity. Following genotoxic insults, the protein level of p53 is increased, and p53 functions as a sequence‐specific transcription factor that regula