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Identification of phosphodiesterase 9A as a cyclic guanosine monophosphate–specific phosphodiesterase in germinal vesicle oocytes: a proposed role in the resumption of meiosis

✍ Scribed by Carol B. Hanna; Shan Yao; Xuemei Wu; Jeffrey T. Jensen

Book ID: 116480495
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 527 KB
Volume: 98
Category: Article
ISSN: 1556-5653
DOI: 10.1016/j.fertnstert.2012.05.015

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## Abstract We report experiments which involve a light sensitive GTPase in the light dependent activation of retinal rod 3′5′‐cyclic guanosine monophosphate (cGMP) phosphodiesterase (PDE). The data suggest that the light activated GTPase is intermediate between rhodopsin and PDE in the light‐depen