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Identification of peptide epitopes of MAGE-1, -2, -3 that demonstrate HLA-A3-specific binding

✍ Scribed by C. A. McIntyre; Robert C. Rees; Kathryn E. Platts; Catherine J. Cooke; M. Olivia Smith; Kevin A. Mulcahy; Anna K. Murray

Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
101 KB
Volume
42
Category
Article
ISSN
0340-7004

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## MAGE -2 is expressed in many tumors, including melanoma, laryngeal tumors, lung tumors and sarcomas, but not in healthy tissue, with the exception of testis. Thus, MAGE-2derived peptides that bind to HLA class I molecules and elicit cytotoxic T lymphocyte (CTL) responses could be of significant