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Identification of penetration enhancers for testosterone transdermal delivery from spray formulations

✍ Scribed by Marie-Laure Leichtnam; Hervé Rolland; Patrick Wüthrich; Richard H. Guy


Book ID
113691211
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
197 KB
Volume
113
Category
Article
ISSN
0168-3659

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✍ Marie-Laure Leichtnam; Hervé Rolland; Patrick Wüthrich; Richard H. Guy 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB

The goal was to explore whether the incorporation of antinucleant polymers into a testosterone spray formulation could stabilize a putative supersaturated state and improve the delivery of the drug across the skin. Several antinucleants were screened using differential scanning calorimetry (DSC) and