Identification of p-nitrophenyl glucoside as a urinary metabolite
โ Scribed by T. Gessner; N. Hamada
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 269 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The urinary metabolites of p-phenoxyphenol methanesulfonate ( I ) in rat and man were characterired. The drug was extensively nietabolired in both cpecies and excreted mainly in the form of conjugated phenolic compounds. The major metabolite of I in both species was identified as the conjugated mono
magnesium sulfate), and the solvent was removed by evaporation under reduced pressure, giving the desired ketone. This procedure was used to isolate 2-piperidinoacetophenone and gave a yield of 91%, bp 102-104' (0.2 mm Hg) [lit. (10) bp 180-181O (26 mm Hg)]; IR: