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Identification of Ostruthin from Peucedanum ostruthium Rhizomes as an Inhibitor of Vascular Smooth Muscle Cell Proliferation

✍ Scribed by Joa, Helge; Vogl, Sylvia; Atanasov, Atanas G.; Zehl, Martin; Nakel, Thomas; Fakhrudin, Nanang; Heiss, Elke H.; Picker, Paolo; Urban, Ernst; Wawrosch, Christoph; Saukel, Johannes; Reznicek, Gottfried; Kopp, Brigitte; Dirsch, Verena M.

Book ID
120462092
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
872 KB
Volume
74
Category
Article
ISSN
0163-3864

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## Abstract Smooth muscle cell (SMC) migration and proliferation are key events in the pathogenesis of atherosclerotic and post‐angioplasty restenotic lesions. Mechanical injury to the artery wall induces the SMC expression of the zinc finger transcription factor, early growth response factor‐1 (Eg