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Identification of off-target binding proteins to elucidate mechanism of drug toxicity

✍ Scribed by Rico Funhoff; Natasa Zamurovic; Axel Vicart; Laure Bouchez; Hans Voshol; Bertran Gerrits; Gregory Guillemain; Laurent Morawiec; Jean-Philippe Gasser


Book ID
116925360
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
104 KB
Volume
211
Category
Article
ISSN
0378-4274

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The mechanisms Involved in the protection by Se against Cd toxicity in the rat were investigated. Se was found to significantly increase the Cd content in the blood and the testis, while decreasing that in the liver and kidney. Se diverted aMost alI the Cd in the sohrbie fraction of the testis from