Identification of Novel Tumor Suppressor Genes Down-Regulated in Recurrent Nasopharyngeal Cancer by DNA Microarray

Imprinted tumor suppressor genes ARHI an

Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation

✍ Weiwei Feng; Rebecca T. Marquez; Zhen Lu; Jinsong Liu; Karen H. Lu; Jean-Pierre 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 618 KB

## Abstract ## BACKGROUND Imprinted tumor suppressor genes may be particularly important in the pathogenesis of ovarian cancer. Two imprinted genes, paternally expressed 3 (__PEG3__) and aplasia Ras homologue member I (__ARHI__), are the most frequently down‐regulated in ovarian cancers on gene ex