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Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells

โœ Scribed by Young-Sook Baek; Stefan Haas; Holger Hackstein; Gregor Bein; Maria Hernandez-Santana; Hans Lehrach; Sascha Sauer; Harald Seitz

Book ID
115004956
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
359 KB
Volume
10
Category
Article
ISSN
1471-2172

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## Abstract We have investigated the effects of sex steroids, estradiol (E2), and testosterone (T) on the synthesis of tumor necrosis factor alpha (TNFโ€ฮฑ) and interleukinโ€10 (ILโ€10) in phorbolโ€myristateโ€acetate (PMA)โ€differentiated human monoblastic U937 cells. The ability of both hormones to modul