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Identification of Novel Candidate Genes for Treatment Response to Risperidone and Susceptibility for Schizophrenia: Integrated Analysis Among Pharmacogenomics, Mouse Expression, and Genetic Case-Control Association Approaches

✍ Scribed by Masashi Ikeda; Yasuyuki Tomita; Akihiro Mouri; Minori Koga; Tomo Okochi; Reiji Yoshimura; Yoshio Yamanouchi; Yoko Kinoshita; Ryota Hashimoto; Hywel J. Williams; Masatoshi Takeda; Jun Nakamura; Toshitaka Nabeshima; Michael J. Owen; Michael C. O'Donovan; Hiroyuki Honda; Tadao Arinami; Norio Ozaki; Nakao Iwata

Book ID: 119198376
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 231 KB
Volume: 67
Category: Article
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2009.08.030

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additional candidate genes are tested in this case-control resource, adjustment for multiple comparisons will become crucial in order to reduce the chance of false positive findings. The ascertainment of auxillary groups of cases and controls with sequential hypothesis testing in these groups offer