## Abstract Cancer/testis (CT) antigens are immunogenic proteins expressed predominantly in gametogenic tissue and cancer; they are considered promising target molecules for cancer vaccines. The identification of new CT genes is essential to the development of polyvalent cancer vaccines designed to
Identification of new genes by systematic analysis of cdnas and database construction
β Scribed by Kenichi Matsubara; Kousaku Okubo
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 610 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0958-1669
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## Abstract Cervical cancer (CC) cells exhibit complex karyotypic alterations, which is consistent with deregulation of numerous critical genes in its formation and progression. To characterize this karyotypic complexity at the molecular level, we used cDNA array comparative genomic hybridization (
cDNA representational difference analysis (cDNA-RDA) is a polymerase-chain-reaction-coupled subtractive and kinetic enrichment procedure for the isolation of differentially expressed genes. In this study, the technique was used to isolate novel genes specifically expressed in pancreatic cancer. cDNA